By Ala F. Nassar
The publication contains eight chapters; it first offers an advent on biotransformation of xenobiotics, after which offers glossy techniques and methods for facing metabolite characterization, utilizing instruments akin to LC-MS, H-D trade, good isotopes LC-MS-NMR, and radiolabeled compounds. additionally, concepts for facing reactive intermediates in drug discovery and improvement are offered in addition to case stories on enhancing the decision-making procedure within the structural amendment of drug applicants. The final bankruptcy discusses the regulatory views of defense checking out of drug metabolites and why, how, and whilst to check their safety.
Read Online or Download Biotransformation and Metabolite Elucidation of Xenobiotics: Characterization and Identification PDF
Similar biotechnology books
A transparent clarification of the reason, analysis, and therapy of diabetes Written for a vast diversity of readers, together with scholars, researchers, policymakers, healthiness care prone, and diabetes sufferers and caregivers, this publication explains the underlying biochemistry and body structure of diabetes mellitus.
This booklet compiles all facets of biomimetics from primary ideas to present technological advances and their destiny tendencies within the improvement of nanoscale biomaterials and tissue engineering. The scope of this ebook is mainly restrained to biologically-inspired layout of fabrics and structures for the advance of subsequent new release nanobiomaterials and tissue engineering.
Written with a various viewers in brain, this booklet describes the present prestige, improvement, and destiny clients for the severe expertise of second-generation biorefineries, particularly with a spotlight on lignocellulosic fabrics as feedstock. It presents an summary of the problems at the back of this technological transition, and it offers, intensive, the technological know-how and expertise regarding cellulose for creation of bioethanol and different biofuels.
The state of the art advances during this examine box are well pictured within the chapters of this quantity. they arrive from world’s major laboratories engaged within the improvement of molecular machines and are authored by means of essentially the most revered scientists within the box. This quantity exhibits, at the one hand, the extent of ingenuity and technical power reached within the building of synthetic nanomachines approximately twenty years after their inception.
- Male Germline Stem Cells: Developmental and Regenerative Potential (Stem Cell Biology and Regenerative Medicine)
- Methods in Bioengineering: 3d Tissue Engineering (The Artech House Methods in Bioengineering)
- Introduction to Biomedical Engineering
- Statistical Modeling and Machine Learning for Molecular Biology (Chapman & Hall/CRC Mathematical and Computational Biology)
Extra info for Biotransformation and Metabolite Elucidation of Xenobiotics: Characterization and Identification
Biotransformation and Metabolite Elucidation of Xenobiotics: Characterization and Identification by Ala F. Nassar